Ashitaba

Angelica Keiskei

Use with CautionDigestive HealthImmune SupportMetabolic Health

Medicinal Facts

Angelica keiskei, commonly known as Ashitaba, is rich in chalcones such as xanthoangelol and 4-hydroxyderricin, which are central to its medicinal properties. It bridges the traditional Japanese Kampo medicine, where it is used for vitality and digestion, and modern research focusing on its anti-inflammatory and metabolic effects. Ashitaba's unique compounds interact with various signaling pathways, including AMPK and NF-kB, offering potential benefits for metabolic health and inflammation. Its broad spectrum of activity is complemented by its role in promoting longevity through sirtuin activation.

What it helps with

Metabolic syndrome

Xanthoangelol and 4-hydroxyderricin activate AMP-activated protein kinase (AMPK), which enhances glucose uptake and fatty acid oxidation. This action improves insulin sensitivity and reduces hepatic lipogenesis, as demonstrated in animal studies and preliminary human trials.

Longevity & cellular aging

Ashitaba's chalcones, particularly xanthoangelol, are shown to activate sirtuin 1 (SIRT1), a key regulator of cellular aging. This activation promotes mitochondrial biogenesis via PGC-1a and may enhance telomere maintenance, although human evidence is still emerging.

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About Ashitaba

Angelica keiskei, commonly known as Ashitaba, is a perennial plant native to Japan, particularly the Izu Islands. It belongs to the Apiaceae family, which includes other well-known herbs such as parsley and celery. Ashitaba is renowned for its vibrant green leaves and yellow sap, which is rich in chalcones, a type of flavonoid with potent antioxidant properties. Traditionally, Ashitaba has been used in Japanese folk medicine for its purported health benefits, including promoting longevity and vitality. It is often consumed as a tea or used in cooking to enhance the nutritional profile of meals. The plant's medicinal properties are largely attributed to its bioactive compounds, such as chalcones, which include xanthoangelol and 4-hydroxyderricin. These compounds are believed to exert anti-inflammatory, antioxidant, and antimicrobial effects. Modern research suggests that Ashitaba may support digestive health by promoting a healthy gut flora and aiding liver detoxification. Additionally, its potential to regulate blood sugar levels makes it a subject of interest for metabolic health studies. While Ashitaba is not as extensively studied as some other medicinal plants, preliminary research indicates its potential in boosting the immune system and providing antiviral benefits. However, its use should be approached with caution, particularly for individuals on anticoagulant medications or those who are pregnant or breastfeeding. As interest in natural remedies grows, Ashitaba continues to be explored for its diverse health-promoting properties.

Traditional Use

Historically, Angelica keiskei has been utilized in traditional Japanese medicine, particularly in the Edo period, where it was celebrated for its health benefits. The name 'Ashitaba' translates to 'tomorrow's leaf,' symbolizing its rapid growth and rejuvenating properties. It has been documented in various herbal texts and is often included in dietary regimens aimed at promoting longevity and vitality. Over time, its use has spread beyond Japan, gaining popularity in other parts of Asia and among health enthusiasts worldwide.

Preparations & Dosage

Preparations

Tea / Infusion: Add 1-2 teaspoons of dried Ashitaba leaves to a cup of boiling water. Allow it to steep for 5-10 minutes. Strain and serve. Optionally, add honey or lemon for taste.
Tincture: Combine fresh or dried Ashitaba leaves with alcohol (such as vodka) in a 1:5 ratio. Seal in a jar and store in a cool, dark place for 4-6 weeks, shaking occasionally. Strain and store in a dark glass bottle.
Capsule: Use commercially prepared Ashitaba capsules. Follow the dosage instructions provided by the manufacturer, typically 500 mg to 1 g per day.

Interactions & Warnings

Angelica keiskei may interact with anticoagulant medications, increasing the risk of bleeding. It should be used cautiously with other herbs that have blood-thinning effects, such as ginkgo biloba and garlic. Individuals with bleeding disorders or those scheduled for surgery should avoid it. High doses may cause gastrointestinal upset or allergic reactions in sensitive individuals.

Use with caution

Angelica keiskei should be used with caution by individuals on blood-thinning medications due to its potential anticoagulant effects. Pregnant or breastfeeding women should avoid it unless advised by a healthcare professional.