antibacterial, antiviral, anti-spirochetal, immunostimulant, anti-inflammatory, central nervous system relaxant, brain and spinal cord protectant, anti-carcinogenic, vasodilator, cardioprotective, antithrombotic, hemostatic and astringent.

certain properties in knotweeds cross the blood-brain barrier where they exert actions on the central nervous system, specifically protecting the brain from inflammatory damage, microbial endotoxins and bacterial infections.
It can enhance blood flow especially to the eye, heart, skin and joints, making it especially helpful in Lyme disease as it facilitates blood flow in hard-to-reach areas to kill the spirochetes. It can be useful in treating the Lyme coinfections of bartonella and neuroborreliosis, Lyme arthritis and post-Lyme syndrome.

As part of its modulating and protective action on the endothelial cells lining blood vessels, Japanese knotweed stimulates the formation of new blood vessels and the healing of damaged ones in areas such as burned skin. it also stops the development of new vessels and blood flow in areas where it should not occur as in tumor formation.

contains high levels of resveratrol and other polyphenols that protect cells from oxidative stress and DNA damage.

Helps prevent age-related cellular degeneration and supports skin health.

Effective against bacteria, fungi, and viruses, including Borrelia burgdorferi, the pathogen responsible for Lyme disease.

promotes genome stability by activating sirtuin (SIRT1) repair mechanisms and can prevent DNA damage from radiation.

https://projectlyme.org/6-herbs-i-use-for-chronic-lyme/

knotweed extract improves memory and reduces brain inflammation.

now if your concern is reducing spike proteins, i would recommend spermidine, resveratrol, & nattokinasse.

Resveratrol primarily mitigates damage caused by spike proteins rather than breaking them down directly.

While resveratrol does not directly degrade spike proteins, it protects cells from the inflammatory and oxidative damage induced by spike protein presence.

It also promotes improved vascular function and immune regulation, helping the body counteract spike protein pathology.

Resveratrol significantly increases the activity of telomerase, the enzyme responsible for adding DNA sequences to the ends of chromosomes (telomeres).
resveratrol helps preserve telomere length and reduces the rate of telomere shortening.
Resveratrol slows down or reverses cellular senescence—the state where cells stop dividing—by preventing the shortening of telomeres and mitigating "senescent memory".

Bohemian knotweed, a cross between Japanese and Sakhalin knotweed, often shows similar, and sometimes higher, levels of phenolic compounds compared to its parent species.

Bohemian knotweed (Fallopia × bohemica) contains significant levels of resveratrol, particularly in its flowers, which have been found to contain up to 476g (micrograms per gram).

The plant produces this compound in response to stress, making it highly concentrated in its roots as a defense mechanism.

While flowers are highest, the rhizomes (roots) also contain measurable, high amounts of resveratrol, which are often used in ethanol extracts for potential pharmaceutical use.

While Japanese knotweed (F. japonica) is more commonly used commercially, Bohemian knotweed (a hybrid) serves as a potent source of this antioxidant, along with high concentrations of compounds like polydatin.

If you're looking to add more resveratrol into your body, go with the bohemian knotweed.

Nattokinase has demonstrated the ability to degrade spike proteins directly, making it one of the most promising compounds for breaking down these proteins.

It also improves blood flow and reduces clot formation, which addresses vascular issues linked to spike proteins.

id recommend taking nattokinase if you’re having heart issues after taking mrna vaccines.

out of the three, you absolutely need nattokinase for directly targeting and breaking down spike proteins, alongside its benefits for cardiovascular health.

Spermidine works by enhancing autophagy, a cellular process where damaged proteins, including potentially harmful spike proteins, are broken down and cleared from cells.

By promoting cellular repair and protein degradation, spermidine indirectly supports the clearance of spike proteins.

more info here:

https://pmc.ncbi.nlm.nih.gov/articles/PMC10222799/

Spermidine aids indirectly by enhancing cellular cleanup through autophagy rather than directly degrading spike proteins, which is still beneficial.