works best for "wet" productive coughs (the kind with thick stagnant phlegm) because marrubiin (the bitter active compound) stimulates your respiratory tract to make more thin, watery secretions. this thins the phlegm and makes it easier to cough up and clear out.
classic horehound candy or syrup form, the bitter taste itself triggers the cough-loosening reflex.
good for productive cough, bronchitis, whooping cough, asthma with thick phlegm, post-cold lingering cough, and chronic smoker's cough.

drink horehound tea or take a horehound bitter formulation 15-20 minutes before meals to wake up your stomach. the intensely bitter taste tells your body to crank out stomach acid, bile, and digestive enzymes.
good for sluggish digestion, poor appetite, bloating after meals, gas, mild gallbladder issues, and indigestion.
not the herb for you if you already have active ulcers. can make existing stomach ulcers WORSE (the bitter principle stimulates acid production). avoid if you have active ulcers.

horehound lowers blood sugar and improves cholesterol. blocks carb-digesting enzymes, improves insulin sensitivity, and protects insulin-producing pancreatic cells.

horehound water extract lowers cholesterol and blood pressure. it helps clear "bad" LDL cholesterol from your blood, prevents arterial plaque buildup, relaxes blood vessels, and even has some heart rhythm-stabilizing activity.

shows real promise for repairing lung scarring (pulmonary fibrosis), a serious condition that's usually considered irreversible.
a 2022 tunisian study showed horehound aqueous extract brought fibrotic rat lungs back close to normal structure. potentially useful for post-COVID lung fibrosis, chemo-induced lung damage (especially from bleomycin), and idiopathic pulmonary fibrosis.

a non-opioid pain reliever, working through COX-2 inhibition similar to NSAIDs. also reduces general inflammation.

kills gram-positive bacteria, gram-negative bacteria, and fungi. also breaks down biofilms (the protective slime layers bacteria build to resist antibiotics). useful as a wound wash, mouthwash, or in respiratory infection support.

protects your liver from chemotherapy drug damage (especially cyclophosphamide), alcohol damage, and chemical toxins. preserves glutathione and reduces liver inflammation.

horehound poultice heals skin ulcers, slow-healing wounds, and skin infections. apply crushed leaves or strong tea to the affected area.

documented as both an emmenagogue (period-bringer) and abortifacient. do not use during pregnancy... unless...