Cuajilote

Aka: Pepino Kat, Cow Okra, Cucumber Tree

its fruit contains over 700 identified metabolites including compounds that fight breast cancer, lower blood sugar — notably including metformin, the world's most prescribed diabetes drug, occurring naturally in the plant — prevent kidney stones, kill bacteria, and feed beneficial gut bacteria.

hexane extract from the fruit induced cytotoxic and apoptotic effects against the breast cancer cell line MDA-MB231.
anticancer compounds identified include genkwanin, hesperidin, and phenylketaldoxime.

a guaianolide, lactucin-8-O-methylacrylate, was isolated from dried fruits. administered intraperitoneally to diabetic mice at 300 mg/kg, blood glucose decreased by 43.75%, and by 29.61% in non-diabetic mice. metformin was identified among the detected metabolites, the same compound used as the most prescribed oral antidiabetic drug globally

extract induced diuretic and antiurolithiatic effects in Wistar rats, supporting the traditional Mayan use for kidney pain and kidney stone prevention. antiurolithiatic means it inhibits or reduces the formation of urinary calculi.

higher antioxidant activity obtained from ethanolic extracts of ripe pulp, with elevated polyphenol content and antibacterial activity also present in ripe pulp extracts.

the fruit tastes like sugarcane and can be eaten raw or cooked.